What Does Skin401 Arbutin 2% Skin Tone Equalizing Anti-Blemish Serum Do? Thanks to the arbutin it contains, it helps reduce the appearance of dark spots and makes the skin look brighter and more even. Thanks to Aloe Vera, it provides moisture to the skin. How to Use Skin401 Arbutin 2% Skin Tone Equalizing Anti-Blemish Serum? It is used twice a day, in the morning and in the evening, on cleansed skin in your skin care routine. Warnings: Not recommended for people with very sensitive skin, eczema and rosacea. Avoid contact with eyes and around the eyes. In case of contact, rinse with plenty of water. It is recommended to try it on a small area of the skin before applying it to avoid allergic reactions.